I had the chance to try Commerce exploits posted above in a new game, and the exploits are a game breaker. I could sell my one synchrotron as many times as I want for infinite money. I do not need colony skills for money when I can exploit that money loop. With infinite money, I can restore everything, and all it costs is a minute or two to sell my synchrotron a few times. With market refresh combined with infinite money, I have effectively infinite crew, supplies, fuel, and anything else my colony produces (like marines and rare metals if I have the industries), plus ships.
Commerce with its bugs is the most powerful industry in the game, if the player has a synchrotron or pristine nanoforge to jump start the infinite money loop. (Corrupted nanoforge could do, but is worth much less and takes much longer to build up money.)