With most skills maxed, this is what I used in 0.65:
Paragon (0.65)
Weapons: Plasma Cannon x2, Tachyon Lance x2, Heavy Needler x2, Heavy Blaster x4, Burst PD Laser x9, Reaper Torpedo x4
Hullmods: Accelerated Shields, Augmented Engines, Auxiliary Thrusters, Integrated Targeting Unit, Resistant Flux Conduits
Capacitors: 0
Vents: 89
Tachyon Lances at side turrets for long range sniping and EMP damage. Plasma Cannons and Heavy Blaster for damage. Heavy Needler for shield buster. Burst PDs for point defense. Reapers with Missile Specialization 10 are one of the most powerful attacks in the game, great for killing obnoxious enemy capitals with Combat 10.
Accelerated Shields because omni shields on capitals raise too slowly. Augmented Engines and ITU because both are just that good and are no-brainers. Auxiliary Thrusters because capital turn too slowly without it. Resistant Flux Conduits for faster venting and shrugging off EMP damage.
I would use four Tachyon Lances and six Heavy Blasters instead of plasma cannons and heavy needlers, but the recent POV change while using Tachyon Lance is intolerable. In 0.62, I used this:
Paragon (0.62)
Weapons: Tachyon Lance x4, Heavy Blaster x6, Burst PD Laser x9, Sabot (single) x4
Hullmods: Accelerated Shields, Augmented Engines, Auxiliary Thrusters, Integrated Targeting Unit, Resistant Flux Conduits
Capacitors: 45
Vents: 50
Back then, I did not go past the mid-forties and get max Flux Dynamics or Missile Specialization or Applied Physics (no Hardened Shields). Also, missiles were slower and I used only single missiles because Optimized Assembly made them free. Back then, I used Tachyon Lances to snipe and shut down enemies while Heavy Blasters did big damage to everything else. This configuration was made to not rely on ammo and fight as long as it takes to win.