Seems like Cryoflammer target leading are bit off.
Same thing happens with the Symbiotic Void Creature's acid flame thrower.
Cryoflamer "projectiles" are scripted to use rope machanics. When the ship rotates, the flame turns with the ship. I'm not sure if it's even possible to predict their path when the ship doesn't rotate, much less when it does. The weapon design is inherently non-aimable. I added it to a blacklist, so that AI tweaks doesn't even attempt to aim the weapon. What you're seeing is vanilla aiming algorithm.
As for the acid flamer, I didn't know it does the same. Though I heard Jannes was implementing rope mechanics, so that's probably it.
So, unfortunately, I won't be able to fix this issue.