It is best used on ships with high armor (which means low-tech) and good PD ability (able to mount sufficient flak or similar weapons). Generally, Onslaught and Dominator. Other cruisers and capitals can make decent use of it, but they are not as good.
Ships without shields need the following hullmods:
* Heavy Armor, for more armor.
* Armored Weapon Mounts, for tougher weapon mounts and more armor.
* Resistant Flux Conduits, for EMP resistance.
(Note: Engines generally do not get shot at too much, so Insulated Engines can be skipped.)
They also need the following skills:
* Impact Mitigation, for less armor damage
* Polarized Armor, for less armor damage and more EMP resistance.
Ships without shields can survive endgame human bounties. They generally die in Ordos fights, although they can survive longer than halfway through the fight.