I run two plasmas in the turrets and front larges empty for the AI quite frequently on paragon (I think the turrets are better due to maneuverability, but I can imagine the small range advantage of the hard points could be relevant). Two plasmas plus medium ballistics is enough to use all the available dissipation (2k+), and I think the Paragon really benefits from not exceeding dissipation by a significant amount, primarily because it has really good shield efficiency and fortress shield which means it can spend its capacity on absorbing incoming fire very efficiently, so spending that capacity on firing weapons over dissipation can be actively bad IMO. I also leave the medium energy spots empty or spend them on PD of some sort. For a player build, I might fill those spots but use them very sparingly, but the AI is not capable of that, so I prefer to just leave the slots empty.
I've found it to be very effective after significant testing personally.
I still think the small missiles on the eradicator are worth filling though lol. 15 OP for 5 breaches is 100% better than 15 capacitors IMO. I've been really enjoying using arblests on the eradicator actually. They have the best shield damage efficiency IIRC, and 200 damage/shot hits quite hard against armor/hull also. They are just a bit mount inefficient and lacking range, but I find they fill out the eradicators DP nicely and match range with the heavy mortar and small ballistics (and thumper).