Hi - sorry about the trouble! So, just to confirm: have you tried manually deleting all the game files (after saving off any screenshots or saves you care about), and then reinstalling? Manually deleting them would just help make absolutely sure this isn't some sort of gamefile corruption issue.
If you've done that, a couple of things to try:
Running the game as administrator (right click on icon, run as administrator)
Running the game incompatibility mode for windows 95 (right click on icon, click properties, go to compatibility tab, the option is there)
Also: have you installed any software recently, or is something now running that wasn't running before? What you're describing could be due to something else that's running interfering with the game. For example, an anti-virus, MSI Afterburner, any kind of video-related software, or even potentially something running in the browser.
All of these are long shots, but *something* on your PC had to have changed for it to go from "working" to "not working". Another possibility is that the graphics drivers autoupdated between then and now, and the new ones have an issue. You did say you updated them, but - potentially, depending on whether the new drivers are the culprit - the solution might be downgrading to the previous version.