the manufacturing in general is a little weird.
it seems like the things the pirates should produce (drugs, organs) are instead produced by independents. the only real source of organs i could find are in nomios, actually. but maybe that's just me not looking hard enough.
it feels like each faction should produce certain things, based on their theme
hegemony: domain starship weapons, supplies in large numbers, starship fuel, heavy machinery (due to autofactories on jangala) experienced crew (due to strong naval tradition)
TT: heavy/exotic energy weaponry, TT ships, crew, high tech equipment (not really represented; heavy machinery sort of counts but less 'industrial') volatiles due to mimir.
pirates: drugs, organs, really the pirate domain considering their wide illegality and high profitability
indies: indies are too wide IMO, it feels like 90% of the sector are "independent" even though they have almost nothing in common. everyone that isn't explicitly someone else just gets jammed in indie. that said, probably ore/rare ore, volatiles and other "raw materials" indies as miners, minor trade syndicates and freeworlds it seems reasonable.
ludd: food, there should probably also be something else; trade goods seem a little sparse IMO.
syndrian: honestly not sure. they need more lore behind them before i could tell you. they seem like a pretty standard military dictatorship at the moment.
on hand weapons i'm not sure. probably everyone because it seems like something everyone would have to manufacture for themselves, while also being necessary.