I'm curious, what is your preferred flagship? I'm not necessarily talking about the biggest, baddest wall-o-guns in the sector (unless that is your preference) but rather what ship do you rely on the majority of the time for your day-to-day combat?
Personally, I'm a huge fan of the Blackrock Driveyards Nevermore. The antimatter lance allows it to remove small targets from the battlefield almost instantly, and to punch far above it's weight class against harder targets. It can also dump flux like it's going out of style. The combination means that it can utterly shred destroyer fleets, and can solo cruiser fleets too so long as they don't have the deployment to get more than two of their heaviest hitters on the field at the same time. Also, the boost ability, while not as powerful as the burn drive of Hegemony ships, is much more versatile and controllable, and enough to get you out of a tight spot in a pinch, or swoop in and kill a venting/overloaded ship that is just out of range. The downside is that the Nevermore has pretty poor point defense options, a 180 degree frontal shield, and weak rear turret coverage, making it very vulnerable to strike fighters.
As long as I avoid heavy carriers, I can run Nevermore almost solo, with just a small freighter for supply support, making it a very profitable ship to run against the majority of fleets in the sector.
How about you guys? What is your preferred ship, and how do you run it? (Solo, raiding fleet, heavy assualt, etc)