I don't know, right now i just tried a tri-tachyon lance Oddysey and barely made it through, but not with losses i would like to take. The Doom just gets out of weapons range too fast for me to catch up and shoot while venting and by the time i get it down, the other phase ships are still at full HP. And again, i find the 'keep the beam on him' trick a bit cheesy, and they should be beatable even without.
As for timing, the Doom can totally dephase and rephase evading tachyon lances to a perfect rate. The moment the weapon heats up to fire, and it really just takes a fraction of a second, the Doom is rephased again.