I recently had a pretty bad experience against a pair of Grinders with those. The UPC doesn't deal a lot of damage to armour, i was able to tank a lot of shots in a battlecruiser, but the EMP effect will eventually shut down the weapons, making a counter-attack difficult. And if you lack the speed and armor to catch the shooter, then things can really get ugly. Fortunately i managed to brute force the enemy flagship while under fire and forcing them to retreat.
While it looks likes the Joyeuse in its appearance, it's actually much closer to the Autopulse, lot of DPS but poor armor penetration. I'm not sure if it's that strong, it is one of the most expensive weapon in the game (34 OP) but perhaps it'll could uses some tweaks on the range and ROF. Haven't encountered many Neutrinos since the last patch, so i'm not too sure.