I at least find it easier to fight upwards, and retreat downwards, and the other two combat scenarios all have you fightinig upwards and retreating downwards. This ofc ignores the part where battle lines break, rotate, or otherwise stop being a nice horizontal line.
In the scenerio, if you retreat upwards, the enemy will mainly be below you, where it is harder to fight because UI. When retreating, you only get an acceleration bonus from your facing, so you generally end up facing away from the retreat direction until you reach it, so the ship faces up, where the UI doesnt get in the way.
I am just suggesting that in the case of a player retreat mission, the entire map gets flipped vertically. You start at the top and retreat down. Enemy comes in from the top and the sides, and chases you downwards.
Again, not a huge issue, but something I find odd and annoying.