The Hound is the best "blockade runner" cargo ship by far -- it can outrun most ships in the game without difficulty.
Hound would be very good as a freighter for dangerous routes. It's fast enough to evade most ships and can defend itself well enough (particularly in groups) to dissuade small time pirates. In fact these very same quality would make it attractive to pirates so you'll expect them to take Hound as prize whenever possible.
That said a blockade running operation would be more complicated than all Hound. You really only need Hound's unique ability for the final leg of the run. For travel between systems it would be better to use a bigger ship, I can see Apogee fulfilling this role. It's fast, can carry plenty of cargo and can fight its way out if a destroyer tries to intercept it.
I could just picture it, Hegemony has placed Corvus III's floating sky cities under embargo. An Apogee, fully laden with contraband jumps in system and makes for the planetary ring, hidden from long range scanners and just outside of the blockade. All the Hounds from the Hidden Base then rendezvous with the Apogee to offload its cargo for the final burn through the blockade down to the atmosphere of the gas giant. Just as the ships are busy transferring cargo a Hegemony Revenue Protection Squadron shows up. Everyone yells "Crap, it's a raid!" and disperse with the Apogee captain having to pull a Han Solo through all the rocks to lose the tail.
All yes, "The Real MacKay", the finest whiskey brewed old fashion style by hard working Luddist farmers. It's so smooth, the Hegemony won't let anyone else have it. Accept no imitations.